It is the largest seizure since the French government banned the resale of protective masks to prioritise their distribution to health workers in the fight against the COVID-19 pandemic.
Two individuals were arrested while they were unloading boxes in Saint-Denis, just north of Paris, a police source said on Sunday.
One of them said he was a business owner and had bought the masks, including 5,000 high protection FFP2 masks, in the Netherlands for a total of 80,000 euros ($87,000).
The masks were to be sold to construction workers for a large profit, according to police.
In March, 32,500 masks from China were seized from a warehouse near Paris and 28,800 masks were discovered in a shop in a district of Chinese wholesalers, also in the Paris region.