Mahamat Said Abdel Kani is facing war crimes and crimes against humanity charges.
The ex-militia commander, was arrested in Bria region and handed over to the ICC on Sunday by officials in the Central African Republic.
The ex-rebel leader will then be informed of the charges against him and his rights under the ICC Rome Statute.
A limited number of people will be allowed in the courtroom due to Covid-19 health measures.
But the session will be broadcast live on the ICC website in French, English and Sango, the official and primary language in the CAR.
The ICC issued a warrant of arrest for Mohamat Said Abdel Kani on 7 January 2019.
He is alleged to have committed the crimes in 2013 in Bangui, after the ouster of President François Bozize.