Four of Mozambique’s 13 provinces have been affected since the infection spread from the capital Maputo on January 5, deputy director of public health Benigna Matsinhe told a press conference.
It is the third consecutive year that Mozambique has suffered a cholera epidemic with the two fatalities reported to be from the Maputo area.
In 2015, 41 people died in one of the country’s worst ever cholera outbreaks.
“We have recorded less cases in recent days, but what worries us is that we have been unable to halt transmission of the illness,” Matsinhe said.
Since the end of last week, the infection has spread in Tete province, on Mozambique’s western border with Zimbabwe and Malawi, with 397 cases reported.
Cholera typically strikes during Mozambique’s rainy season, between October and March, when unhygienic conditions and stagnant water cause the bacteria to flourish.
The infection can cause severe diarrhoea, dehydration and in the worst cases, death.
Mozambique has been been deluged by heavy rains since October following two years of drought.